Mitochondria-targeted tetrapeptide, cardiolipin & bioenergetics research
$5810 mg vial
≥98% HPLC PurityThird-Party TestedCOA per BatchCold-Chain Ship
About this compound
SS-31, also known as elamipretide or MTP-131, is a small mitochondria-targeted tetrapeptide with the sequence D-Arg-2,6-dimethyltyrosine-Lys-Phe-NH2. Its alternating aromatic-cationic residue pattern allows it to concentrate at the inner mitochondrial membrane, where it selectively associates with cardiolipin, a phospholipid central to inner-membrane architecture and electron transport chain organization.
Research interest in SS-31 centers on mitochondrial bioenergetics, including electron transport chain function, ATP synthesis efficiency, and the reactive oxygen species generated during oxidative phosphorylation. Its cardiolipin-binding mechanism has made it a widely used tool compound in cell and tissue models of mitochondrial dysfunction.
Supplied as a sterile lyophilized powder. Reconstitute with bacteriostatic water for in vitro laboratory use only. Not for human or veterinary administration.
Specifications
CAS Number
736992-21-5
Sequence
D-Arg-2,6-Dmt-Lys-Phe-NH2
Mechanism
Cardiolipin-binding, inner mitochondrial membrane
Purity
≥98% (HPLC)
Form
Lyophilized white powder
Storage (unopened)
-20°C, protected from light
Storage (reconstituted)
2-8°C, use within 30 days
Vial Size
10 mg
Reconstitution & storage
Add 1 mL of bacteriostatic water to the 10 mg vial for a 10 mg/mL working concentration. Swirl gently, do not shake. Refrigerate (2-8°C) once reconstituted and use within 30 days. Protect from light.
Selected research references
Szeto HH. "First-in-class cardiolipin-protective compound as a therapeutic agent to restore mitochondrial bioenergetics." Br J Pharmacol. 2014;171(8):2029-2050.
Birk AV et al. "The mitochondrial-targeted compound SS-31 re-energizes ischemic mitochondria by interacting with cardiolipin." J Am Soc Nephrol. 2013;24(8):1250-1261.
Siegel MP et al. "Mitochondrial-targeted peptide rapidly improves mitochondrial energetics and skeletal muscle performance in aged mice." Aging Cell. 2013;12(5):763-771.
References listed for research-context only. Norway Peptides does not endorse, sponsor, or financially benefit from any cited work. Researchers should consult primary sources directly.
Effective May 1, 2026
These Terms of Sale govern all purchases of products from Norway Peptides ("Norway Peptides," "we," "us," or "our"). By placing an order through this website or any affiliated channel, you ("Buyer") agree to be bound by these Terms.
1. Eligibility and Buyer Representation
Norway Peptides sells exclusively to qualified research professionals and institutions for laboratory research and educational use. By placing an order, Buyer represents and warrants that Buyer is at least 21 years of age, is a qualified researcher or authorized representative of a research institution, and will use the products solely for in vitro laboratory research. Norway Peptides reserves the right to refuse or cancel any order at its sole discretion.
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Effective May 1, 2026
This Research Use Policy describes the conditions under which Norway Peptides supplies research-grade peptides and related compounds (collectively, "Products"). By purchasing, receiving, or using any Product, Buyer agrees to comply with this Policy in addition to our Terms of Sale.
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