Mitochondrial-derived peptide, AMPK activation & metabolic homeostasis research
$4810 mg vial
≥98% HPLC PurityThird-Party TestedCOA per BatchCold-Chain Ship
About this compound
MOTS-c is a 16-amino-acid mitochondrial-derived peptide (MDP) encoded within a short open reading frame of the mitochondrial 12S rRNA region, distinct from the nuclear genome-encoded peptides typically studied in metabolic research. It was identified as part of a class of mitochondrial-encoded signaling peptides that communicate metabolic status between mitochondria and the rest of the cell.
Research interest centers on MOTS-c's activation of the AMPK pathway, a central regulator of cellular energy balance, and its downstream effects on glucose uptake, insulin sensitivity, and metabolic homeostasis in cell and animal models. Because AMPK activation is also triggered by exercise, MOTS-c is frequently studied as an exercise-mimetic tool compound for investigating skeletal muscle metabolism and mitochondrial-nuclear communication under metabolic stress.
Supplied as a sterile lyophilized powder. Reconstitute with bacteriostatic water for in vitro laboratory use only. Not for human or veterinary administration.
Specifications
Peptide Length
16 amino acids
Classification
Mitochondrial-derived peptide (MDP)
Research Pathway
AMPK activation, metabolic homeostasis
Purity
≥98% (HPLC)
Form
Lyophilized white powder
Storage (unopened)
-20°C, protected from light
Storage (reconstituted)
2-8°C, use within 30 days
Vial Size
10 mg
Reconstitution & storage
Add 1 mL of bacteriostatic water to the 10 mg vial for a 10 mg/mL working concentration. Swirl gently, do not shake. Refrigerate (2-8°C) once reconstituted and use within 30 days. Protect from light.
Selected research references
Peer-reviewed literature on this compound is available through PubMed and primary journals; Norway Peptides does not endorse or benefit from any cited work.
References listed for research-context only. Norway Peptides does not endorse, sponsor, or financially benefit from any cited work. Researchers should consult primary sources directly.
Effective May 1, 2026
These Terms of Sale govern all purchases of products from Norway Peptides ("Norway Peptides," "we," "us," or "our"). By placing an order through this website or any affiliated channel, you ("Buyer") agree to be bound by these Terms.
1. Eligibility and Buyer Representation
Norway Peptides sells exclusively to qualified research professionals and institutions for laboratory research and educational use. By placing an order, Buyer represents and warrants that Buyer is at least 21 years of age, is a qualified researcher or authorized representative of a research institution, and will use the products solely for in vitro laboratory research. Norway Peptides reserves the right to refuse or cancel any order at its sole discretion.
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Effective May 1, 2026
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Buyer is at least 21 years of age
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Effective May 1, 2026
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