Copper(II) tripeptide complex, extracellular matrix & tissue-repair signaling research
$48100 mg vial
≥98% HPLC PurityThird-Party TestedCOA per BatchCold-Chain Ship
About this compound
GHK-Cu is the copper(II) complex of the naturally occurring tripeptide glycyl-L-histidyl-L-lysine (GHK), formed when the tripeptide binds copper ions in a 1:1 coordination complex. In research settings, GHK-Cu is used to study extracellular matrix remodeling, including its influence on fibroblast signaling and the expression of proteins involved in collagen synthesis and tissue-repair pathways.
Investigators have used GHK-Cu as a tool compound in skin and connective-tissue research, examining its role in modulating matrix metalloproteinase activity and cellular signaling cascades associated with wound-healing models. Its well-characterized copper-binding chemistry makes it a useful reference peptide for studies of copper-dependent biological processes.
Supplied as a sterile lyophilized powder. Reconstitute with bacteriostatic water for in vitro laboratory use only. Not for human or veterinary administration.
Specifications
Molecular Formula
C₁₄H₂₄CuN₆O₄
CAS Number
89030-95-5
Sequence
Gly-His-Lys, Cu(II) complex
Purity
≥98% (HPLC)
Form
Lyophilized blue powder
Storage (unopened)
-20°C, protected from light
Storage (reconstituted)
2-8°C, use within 30 days
Vial Size
100 mg
Reconstitution & storage
Add bacteriostatic water to the 100 mg vial to reach the desired working concentration for your protocol. Swirl gently, do not shake. Refrigerate (2-8°C) once reconstituted and use within 30 days. Protect from light.
Selected research references
Pickart L, Margolina A. "Regenerative and Protective Actions of the GHK-Cu Peptide in the Light of the New Gene Data." Int J Mol Sci. 2018;19(7):1987.
Pickart L, Vasquez-Soltero JM, Margolina A. "GHK Peptide as a Natural Modulator of Multiple Cellular Pathways in Skin Regeneration." Biomed Res Int. 2015;2015:648108.
Maquart FX et al. "Stimulation of collagen synthesis in fibroblast cultures by the tripeptide-copper complex glycyl-L-histidyl-L-lysine-Cu2+." FEBS Lett. 1988;238(2):343-346.
References listed for research-context only. Norway Peptides does not endorse, sponsor, or financially benefit from any cited work. Researchers should consult primary sources directly.
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